By Steven B. Karch

ISBN-10: 0849340195

ISBN-13: 9780849340192

A quick background of Cocaine is a completely researched, attention-grabbing account of the position cocaine has performed in all over the world heritage, politics, economics, and technology. shuttle with bestselling writer Steven B. Karch as he strains the trail of cocaine from the coca money vegetation of Spain to the distinguished pharmaceutical homes of Amsterdam into the banking of Japan. know about experimentation with the drug in the course of the centuries, together with the paintings of Sigmund Freud, who instructed that cocaine be used to regard morphine dependancy. detect how cocaine has been grown, subtle, disbursed, and abused worldwide for 4 centuries. ultimately, comprehend why the cocaine alternate is still a thriving company regardless of govt legislation. an important research of an age-old challenge, a short heritage of Cocaine locations the "war on drugs" in its old context and predicts if we're destined to lose.

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Wren was interested in medical problems long before he became an illustrator for Willis. According to the history of the Royal Society, when Wren was a professor of Astronomy at Gresham College, Oxford, in 1656, he began a series of experiments that involved giving intravenous opium injections to dogs. fm Page 48 Monday, August 22, 2005 9:42 AM 48 A Brief History of Cocaine, Second Edition bladder that he filled with an opium solution. All of the experimental animals survived, and Wren was so encouraged by his preliminary results that he decided to repeat the experiment on a man.

In 1882, the placebo effect was not yet recognized. Surgeon-Major T. ” Charles argued that a particularly famous military disaster in Afghanistan could have been averted if the troops were supplied with coca. This preoccupation with endurance culminated with the publication of a paper from a German author that described what happened when a military surgeon secretly added cocaine to the drinking water of Prussian artillerymen. ). An Austrian, Aschenbrandt studied pharmacology in Würzburg from 1891 to 1892.

This means that the addiction potential is much lower. The oral use of opium had built-in safeguards that made addiction less likely and toxicity harder to produce. The safeguards were partially eliminated when morphine, the active ingredient of opium, was successfully isolated from opium, by Friedrich Wilhelm Sertürner, in 1805. In that year, Sertürner announced that he had isolated an alkaline base in opium that he called morphium. The event marked an important milestone for organic chemistry, and not just for addicts.

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A Brief History of Cocaine by Steven B. Karch


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